Solution modality / Radiopharmaceuticals

Match targeted radiation to a biological opportunity.

Binding, tissue distribution and radiation dose must be considered together. Radiopharmaceuticals are in BioTwin’s planned solution space, with a modality-specific design workflow still to be developed.

Current work Planned coverage

Discuss this research direction Compare solution modalities

Why consider this modality?

Determine whether this modality merits investigation and identify the evidence and specialist methods required for an evaluation.

Planned platform coverage

  • In BioTwin today · Radiopharmaceuticals are included in BioTwin's planned solution space.
  • Development and validation · A future development workflow would need target binding, isotope and chelator selection, distribution and dosimetry. Current coverage identifies the research direction; a radiopharmaceutical design workflow is not yet established.

Specialist methods required for development

Define the target and desired effect. A focused research collaboration would need specialist binding, isotope, chelator, distribution and dosimetry methods before a radiopharmaceutical design workflow could be established.

Related exposure modeling

Related research methods to explore; a combined modality-specific workflow is not yet established.

  • Mechanistic Barrier and PBPK Modeling · Investigate the absorption, barrier or compartment-exposure assumption that could determine a program’s next experiment. Read the method

Discuss Radiopharmaceuticals for your program

Start with the biological objective and the decision you need to make. We can establish which existing methods fit and what additional development would be required.

Discuss the research scope