Scientific capability / Target-specific covalent design

Find the chemical constraints that matter for your target.

BioTwin brings molecular recognition, reaction conditions and exposure into the same candidate-design question. Its computational studies help compare alternatives and identify the laboratory measurements that would most change a development decision.

Current work Computational design studies

Illustration of a small molecule near an exposed chemical group on a protein surface.

Compare candidates in their biological context

A promising interaction must remain useful under the conditions in which a drug would operate. BioTwin helps examine the assumptions behind a design and prioritize candidates for further testing.

Turn a molecular hypothesis into a focused experiment

The output is a candidate rationale and a proposed verification plan. Productive engagement, selectivity and biological activity are established through laboratory measurements.

Review the evidence for your decision

Bring a target and the question holding up your program. We can discuss the relevant capabilities and agree a confidential review of selected methods and supporting results.

Discuss a candidate-design question

Bring a target and the question holding up your program. We can discuss the relevant capabilities and agree a confidential review of selected methods and supporting results.